Tolerance & dependence

Tolerance

Hallucinogens are rarely used daily or regularly but when they are, tolerance develops quickly. Tolerance means that higher amounts need to be taken to get the same effect as before. With repeated daily use over three to four days, the desired effects tend to cease irrespective of the amount used. Any tolerance developed quickly goes away once regular use is stopped.

Dependence

Some regular users develop a psychological dependence. They have a strong desire to continue to use hallucinogens because they have become important in their daily lives. If they can't get the drug they may panic or become anxious.